Wolf Blitzer delivers the most important breaking news and political, international, and national security stories of the day. Tune to The Situation Room weekdays 5-7pm ET on CNN.
President Obama sends a letter to Iran's Supreme Leader seeking cooperation against ISIS. Jim Sciutto reports.
Michelle Kosinski looks at what the Democrats loss of the Senate might mean for President Obama's final two years in office.
Is President Barack Obama helping or hindering the message for campaigning Democrats? Michelle Kosinski reports.
Rep. Peter King discusses the federal response to Ebola in the U.S. and President Obama's appointment of an "Ebola czar".
U.S. and British officials have released statements condemning the brutal beheading of British aid working Alan Henning.
As the director of the Secret Service resigns amidst a security breach, the administration starts to seek a replacement.
Wolf Blitzer talks to White House Press Secretary Josh Earnest reacts to the House vote to arm Syrian rebels in the fight against ISIS.
President Obama visited the U.S. Central Command, which is planning the current airstrike campaign in Iraq.
Wolf Blitzer asks Sen. Bernie Sanders if he agrees with Obama's ISIS strategy & when he will announce if he's running in 2016.
Are we at war with ISIS? As Michelle Kosinski reports, it depends on who you ask in the Obama administration.